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American Society of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, 5(65), p. 614-622, 2001

DOI: 10.4269/ajtmh.2001.65.614

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Factors Contributing to Anemia After Uncomplicated Falciparum Malaria

Journal article published in 2001 by Ric N. Price, Christine Luxemburger, Julie A. Simpson ORCID, Lili Hkirjaroen, François Nosten, Feiko Ter Kuile, Nicholas J. White, Tan Chongsuphajaisiddhi, F. ter Kuile
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The factors contributing to anemia in falciparum malaria were characterized in 4,007 prospectively studied patients on the western border of Thailand. Of these, 727 patients (18%) presented with anemia (haematocrit 2 days) before admission, and pure Plasmodium falciparum infections rather than mixed P. falciparum and Plasmodium vivax infections. The mean maximum fractional fall in hematocrit after antimalarial treatment was 14.1% of the baseline value (95% confidence interval [CI], 13.6–14.6). This reduction was significantly greater in young children (aged