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IOS Press, Journal of Huntington's Disease, 1(2), p. 125-134, 2013

DOI: 10.3233/jhd-130049

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A Critical Evaluation of Inflammatory Markers in Huntington's Disease Plasma

Journal article published in 2012 by Edina Silajdzic, Ej Wild, Melinda Rezeli, Ákos Végvári, A. Végvári ORCID, Nayana Lahiri, Ralph Andre, Anna Magnusson-Lind, Rajasree Nambron, Eirini Kalliolia, György Marko-Varga, Thomas Tt Warner, Thomas Laurell, Sj J. Tabrizi, Maria Bjorkqvist
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Huntington's Disease (HD) is a hereditary, progressive neurodegenerative disorder characterised by both neurological and systemic symptoms. In HD, immune changes can be observed before the onset of overt clinical features raising the possibility that inflammatory markers in plasma could be used to track disease progression. It has previously been demonstrated that a widespread, progressive innate immune response is detectable in plasma throughout the course of HD.