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Elsevier, Biochemical and Biophysical Research Communications, 3(188), p. 1090-1096, 1992

DOI: 10.1016/0006-291x(92)91343-o

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Glutathione inhibits replication and expression of viral proteins in cultured cells infected with sendai virus

Journal article published in 1992 by E. Garaci, A. T. Palamara ORCID, P. Di Francesco, C. Favalli, M. R. Ciriolo, Ciriolo Mr., G. Rotilio
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Addition of reduced glutathione inhibited the production of Sendai virus in African green monkey kidney (AGMK) cells. This result could be accounted for by a direct action of GSH on viral replication. The inhibitory action was associated to an increase of the GSH intracellular level, while the host cell metabolism was unaffected. The antiviral effect was related to decrease and inactivation of the hemagglutinin-neuraminidase (HN) virus glycoprotein.