Published in

Elsevier, Neuroimaging Clinics of North America, 2(21), p. 327-344

DOI: 10.1016/j.nic.2011.02.008

Links

Tools

Export citation

Search in Google Scholar

Imaging Stroke Patients with Unclear Onset Times

Journal article published in 2011 by Ona Wu ORCID, Lee H. Schwamm ORCID, A. Gregory Sorensen, A. Gregory Sorensen
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Despite significant progress in stroke prevention and acute treatment, stroke remains a leading cause of death and adult morbidity worldwide. By defining “stroke symptom onset” in the most conservative manner, namely the time the patient was last known to be well, many patients whose onsets are unwitnessed are automatically ineligible for thrombolytic therapy even if their true time of onset would make them eligible. Many groups are trying to determine if advanced brain imaging can serve as a substitute “witness” to estimate stroke onset and duration in those patients who do not have a human witness. We review and compare some of these imaging-based approaches to thrombolysis eligbility, which if successful, can potentially expand the use of thrombolytic therapy to a broader stroke patient population.