Published in

Association for Research in Vision and Ophthalmology, Investigative Ophthalmology & Visual Science, 6(52), p. 3874

DOI: 10.1167/iovs.10-6029

Links

Tools

Export citation

Search in Google Scholar

Endothelin 1 Stimulates Ca<sup>2+</sup>-Sparks and Oscillations in Retinal Arteriolar Myocytes via IP<sub>3</sub>R and RyR-Dependent Ca<sup>2+</sup>Release

Journal article published in 2011 by James Tumelty, Kevin Hinds, Peter Bankhead ORCID, Neil J. McGeown, C. Norman Scholfield, Tim M. Curtis, J. Graham McGeown
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Red circle
Postprint: archiving forbidden
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Et1-dependent Ca2+-signaling was investigated at the cellular level in retinal vascular smooth muscle. ET1 increased Ca2+-sparks and asynchronous phasic Ca2+-oscillations. This “digital,” frequency-modulated signaling was not previously apparent in microfluorometry recordings of average [Ca2+]i.