Published in
Springer Verlag, Psychopharmacology, 1(213), p. 53-60
DOI: 10.1007/s00213-010-2012-7
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The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys
Journal article published in 2010 by
Christopher A. Podlesnik,
Mei-Chuan Ko 
,
Gail Winger,
Jürgen Wichmann,
Eric P. Prinssen,
James H. Woods
,
Gail Winger,
Jürgen Wichmann,
Eric P. Prinssen,
James H. Woods
This paper is available in a repository.
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Abstract
The synthetic nonpeptide NOP (nociceptin/orphanin FQ peptide) receptor agonist Ro 64-6198 produces antinociception in rhesus monkeys. In rodents, it has much more variable effects on pain responses, but has response rate-increasing effects on punished operant behavior and decreases drug reward.