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EMBO Press, The EMBO Journal, 4(30), p. 719-730, 2011

DOI: 10.1038/emboj.2010.357

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PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity

Journal article published in 2011 by Yasuko Nakamura, Catherine L. Wood, Andrew P. Patton ORCID, Nadia Jaafari, Jeremy M. Henley, Jack R. Mellor, Jonathan G. Hanley
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Dendritic spine remodelling involves regulated actin dynamics and is essential for synaptic plasticity. The Arp2/3 inhibitor PICK1 is here shown to regulate spine size: inducing shrinkage during long-term depression.