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Taylor and Francis Group, OncoImmunology, 2(1), p. 242-243

DOI: 10.4161/onci.1.2.18204

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What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?

Journal article published in 2012 by Denise Nardelli-Haefliger ORCID, Pedro Romero, Patrice Jichlinski
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Tumor-regressions following tumor-associated-antigen vaccination in animal models contrast with the limited clinical outcomes in cancer patients. Most animal studies however used subcutaneous-tumor-models and questions arise as whether these are relevant for tumors growing in mucosae; whether specific mucosal-homing instructions are required; and how this may be influenced by the tumor.