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- [www.ncbi.nlm.nih.gov] | PDF
Tools
Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas
Journal article published in 2006 by
Eric W. Deutsch 
,
Daniel D. Martin,
Nichole L. King,
Jeffrey A. Ranish,
Alexey I. Nesvizhskii,
James S. Eddes,
Parag Mallick,
Jimmy Eng,
Frank Desiere,
Mark Flory,
Bong Kim,
Daniel B. Martin,
Hookeun Lee,
Rudolf Aebersold,
Brian Raught
,
Daniel D. Martin,
Nichole L. King,
Jeffrey A. Ranish,
Alexey I. Nesvizhskii,
James S. Eddes,
Parag Mallick,
Jimmy Eng,
Frank Desiere,
Mark Flory,
Bong Kim,
Daniel B. Martin,
Hookeun Lee,
Rudolf Aebersold,
Brian Raught
Abstract
AbstractWe present the Saccharomyces cerevisiae PeptideAtlas composed from 47 diverse experiments and 4.9 million tandem mass spectra. The observed peptides align to 61% of Saccharomyces Genome Database (SGD) open reading frames (ORFs), 49% of the uncharacterized SGD ORFs, 54% of S. cerevisiae ORFs with a Gene Ontology annotation of 'molecular function unknown', and 76% of ORFs with Gene names. We highlight the use of this resource for data mining, construction of high quality lists for targeted proteomics, validation of proteins, and software development.