Published in
BioMed Central, BMC Bioinformatics, 1(12), 2011
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Estimation of allele frequency and association mapping using next-generation sequencing data
Journal article published in 2011 by
Su Yeon Kim,
Kirk E. Lohmueller,
Anders Albrechtsen 
,
Yingrui Li,
Thorfinn Sand Korneliussen ,
Geng Tian,
Niels Grarup ,
Tao Jiang,
Gitte Andersen,
Daniel Witte ,
Torben Jorgensen,
Torben Hansen,
Oluf Pedersen,
Jun Wang,
Rasmus Nielsen
,
Yingrui Li,
Thorfinn Sand Korneliussen ,
Geng Tian,
Niels Grarup ,
Tao Jiang,
Gitte Andersen,
Daniel Witte ,
Torben Jorgensen,
Torben Hansen,
Oluf Pedersen,
Jun Wang,
Rasmus Nielsen
This paper is made freely available by the publisher.
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Abstract
Abstract Background Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g.,