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Elsevier, Atherosclerosis, 1(219), p. 109-115, 2011

DOI: 10.1016/j.atherosclerosis.2011.07.023

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Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

► Leoligin significantly activated CETP in human plasma at 100 pM. ► Leoligin concentrations of 1 mM inhibited CETP activity. ► There was no short-term toxicity apparent in mice treated with leoligin.