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American Physiological Society, Physiology, 4(29), p. 242-249, 2014

DOI: 10.1152/physiol.00042.2013

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The Myoendothelial Junction: Connections That Deliver the Message

Journal article published in 2014 by Adam C. Straub ORCID, Angela C. Zeigler, Brant E. Isakson
This paper is available in a repository.
This paper is available in a repository.

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Abstract

A vast amount of investigation has centered on how the endothelium and smooth muscle communicate. From this evidence, myoendothelial junctions have emerged as critical anatomical structures to regulate heterocellular cross talk. Indeed, there is now evidence that the myoendothelial junction serves as a signaling microdomain to organize proteins used to facilitate vascular heterocellular communication. This review highlights the evolving role of myoendothelial junctions in the context of vascular cell-cell communication.