Published in
Wiley, International Journal of Cancer, 2(136), p. 360-371, 2014
DOI: 10.1002/ijc.28986
BMJ Publishing Group, Occupational and Environmental Medicine, Suppl 1(71), p. A27.2-A27, 2014
DOI: 10.1136/oemed-2014-102362.84
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- [hal-riip.archives-ouvertes.fr] | PDF
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- [tspace.library.utoronto.ca] | PDF
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- [oem.bmj.com] | PDF
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Lung cancer risk among bricklayers in a pooled analysis of case-control studies
,
Hans Kromhout,
Susan Peters,
Roel C. H. Vermeulen,
Beate Pesch,
Thomas Bruening,
Thomas Brüning,
Benjamin Kendzia,
Thomas Behrens,
Isabelle Stuecker
and other authors.
Full text: Download
Abstract
Bricklayers may be exposed to several lung carcinogens, including crystalline silica and asbestos. Previous studies that analyzed lung cancer risk among these workers had several study design limitations. We examined lung cancer risk among bricklayers within SYNERGY, a large international pooled analysis of case-control studies on lung cancer and the joint effects of occupational carcinogens. For men ever employed as bricklayers we estimated odds ratios (OR) and 95% confidence intervals (CI) adjusted for study center, age, lifetime smoking history and employment in occupations with exposures to known or suspected lung carcinogens. Among 15,608 cases and 18,531 controls, there were 695 cases and 469 controls who had ever worked as bricklayers (OR: 1.47; 95% CI: 1.28-1.68). In studies using population controls the OR was 1.55 (95% CI: 1.32-1.81, 540/349 cases/controls), while it was 1.24 (95% CI: 0.93-1.64, 155/120 cases/controls) in hospital-based studies. There was a clear positive trend with length of employment (p