Cell Press, Cell Metabolism, 3(15), p. 273-274, 2012
DOI: 10.1016/j.cmet.2012.02.008
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Autophagy is generally considered to be a cytoprotective response to stress, whether in the form of nutrient deprivation or the presence of dysfunctional organelles. He et al. now show in Nature that exercise-induced autophagy is needed for some of the beneficial effects of exercise on metabolism (He et al., 2012).