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Oxford University Press (OUP), Bioinformatics, 14(29), p. 1821-1822

DOI: 10.1093/bioinformatics/btt289

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TiPs: a database of therapeutic targets in pathogens and associated tools

Journal article published in 2013 by Rosalba Lepore ORCID, Anna Tramontano, Allegra Via
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

MOTIVATION: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. AVAILABILITY AND IMPLEMENTATION: The TiPs database is freely available at http://biocomputing.it/tips. CONTACT: anna.tramontano@uniroma1.it or allegra.via@uniroma1.it.