Published in

Oxford University Press (OUP), Bioinformatics, 14(29), p. 1840-1841

DOI: 10.1093/bioinformatics/btt276

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TANGO: a generic tool for high-throughput 3D image analysis for studying nuclear organization

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Motivation: The cell nucleus is a highly organized cellular organelle that contains the genetic material. The study of nuclear architecture has become an important field of cellular biology. Extracting quantitative data from 3D fluorescence imaging helps understand the functions of different nuclear compartments. However, such approaches are limited by the requirement for processing and analyzing large sets of images.