Aims. LYRA, the Large Yield Radiometer, is a vacuum ultraviolet (VUV) solar radiometer, planned to be launched in November 2009 on the European Space Agency PROBA2, the Project for On-Board Autonomy spacecraft. Methods: The instrument was radiometrically calibrated in the radiometry laboratory of the Physikalisch-Technische Bundesanstalt (PTB) at the Berlin Electron Storage ring for SYnchroton radiation (BESSY II). The calibration was done using monochromatized synchrotron radiation at PTB's VUV and soft X-ray radiometry beamlines using reference detectors calibrated with the help of an electrical substitution radiometer as the primary detector standard. Results: A total relative uncertainty of the radiometric calibration of the LYRA instrument between 1 and 11 was achieved. LYRA will provide irradiance data of the Sun in four UV passbands and with high temporal resolution down to 10 ms. The present state of the LYRA pre-flight calibration is presented as well as the expected instrument performance.