Published in
Royal Society of Chemistry, RSC Advances, 10(6), p. 7990-7998, 2016
DOI: 10.1039/c5ra26175a
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A non-zipper-like tetrameric coiled coil promotes membrane fusion
Journal article published in 2016 by
Tingting Zheng,
Monica I. Bulacu,
Geert A. Daudey 
,
Frank Versluis,
Jens Voskuhl,
Giuliana Martelli,
Jan Raap,
G. J. Agur Sevink,
Alexander Kros ,
Aimee L. Boyle
,
Frank Versluis,
Jens Voskuhl,
Giuliana Martelli,
Jan Raap,
G. J. Agur Sevink,
Alexander Kros ,
Aimee L. Boyle
This paper is made freely available by the publisher.
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Abstract
A parallel heterodimeric coiled coil can be mutated to an antiparallel tetrameric species by reversing the sequences of one of the peptides. This tetramer is capable of facilitating fast, efficient, membrane fusion of liposomes.