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Public Library of Science, PLoS ONE, 3(7), p. e30909, 2012

DOI: 10.1371/journal.pone.0030909

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Response Inhibition during Cue Reactivity in Problem Gamblers: An fMRI Study

Journal article published in 2012 by Ruth J. van Holst, Mieke van Holstein ORCID, Wim van den Brink, Dick J. Veltman, Anna E. Goudriaan
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Disinhibition over drug use, enhanced salience of drug use and decreased salience of natural reinforcers are thought to play an important role substance dependence. Whether this is also true for pathological gambling is unclear. To understand the effects of affective stimuli on response inhibition in problem gamblers (PRGs), we designed an affective Go/Nogo to examine the interaction between response inhibition and salience attribution in 16 PRGs and 15 healthy controls (HCs).