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Wiley, Journal of Medical Virology, 1(54), p. 7-11, 1998

DOI: 10.1002/(sici)1096-9071(199801)54:1<7::aid-jmv2>3.0.co;2-b

Wiley, Journal of Medical Virology, 1(54), p. 7-11

DOI: 10.1002/(sici)1096-9071(199801)54:1<7::aid-jmv2>3.3.co;2-9

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Characteristics of hepatitis C virus before and after interferon treatment in patients with ongoing viraemia but sustained biochemical response

Journal article published in 1998 by Elena Donadel, Patrizia Pontisso ORCID, Maria Grazia Ruvoletto, Martina Gerotto, Gianluca L. De Salvo ORCID, Liliana Chemello, Carla Casarin, Alfredo Alberti
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

In hepatitis C virus (HCV) infection, persistent viraemia can occur after successful biochemical response to interferon treatment. To assess whether this unusual profile might be due to trivial amounts of remaining virus or to the emergence of less pathogenic HCV strains, pre- and posttreatment sera from 27 patients who remained with HCV-RNA, despite sustained transaminase normalisation after interferon therapy, were investigated. All but one had infection by genotype 2 (P