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Sociedade Brasileira de Cardiologia - SBC, Arquivos Brasileiros de Cardiologia, 2014

DOI: 10.5935/abc.20140152

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Impact of Atrial Fibrillation Ablation on Left Ventricular Filling Pressure and Left Atrial Remodeling

Journal article published in 2014 by Simone Nascimento dos Santos, Marcus Vinícius Nascimento dos Santos, Simone Nascimento Dos Santos ORCID, Santos,Simone Nascimento Dos, Benhur Davi Henz, André Rodrigues Zanatta, Henz,Benhur Davi, Zanatta,André Rodrigues, José Roberto Barreto, Barreto,José Roberto, Loureiro,Kelly Bianca, Kelly Bianca Loureiro, Novakoski,Clarissa, Clarissa Novakoski, Marcus Vinícius Nascimento Dos Santos and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background: Left ventricular (LV) diastolic dysfunction is associated with new-onset atrial fibrillation (AF), and the estimation of elevated LV filling pressures by E/e' ratio is related to worse outcomes in patients with AF. However, it is unknown if restoring sinus rhythm reverses this process. Objective: To evaluate the impact of AF ablation on estimated LV filling pressure. Methods: A total of 141 patients underwent radiofrequency (RF) ablation to treat drug-refractory AF. Transthoracic echocardiography was performed 30 days before and 12 months after ablation. LV functional parameters, left atrial volume index (LAVind), and transmitral pulsed and mitral annulus tissue Doppler (e' and E/e') were assessed. Paroxysmal AF was present in 18 patients, persistent AF was present in 102 patients, and long-standing persistent AF in 21 patients. Follow-up included electrocardiographic examination and 24-h Holter monitoring at 3, 6, and 12 months after ablation. Results: One hundred seventeen patients (82.9%) were free of AF during the follow-up (average, 18 ± 5 months). LAVind reduced in the successful group (30.2 mL/m2 ± 10.6 mL/m2 to 22.6 mL/m2 ± 1.1 mL/m2, p