Published in

American Society for Microbiology, Journal of Clinical Microbiology, 4(41), p. 1794-1797, 2003

DOI: 10.1128/jcm.41.4.1794-1797.2003

Links

Tools

Export citation

Search in Google Scholar

drs (Distantly Related sic) Gene Polymorphisms among emm12-Type Streptococcus pyogenes Isolates

Journal article published in 2003 by Claudia M. Brandt, Gerhard Haase, Barbara Spellerberg ORCID, Regina Holland, Rudolf Lütticken
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

ABSTRACT Twenty-eight emm12 -type Streptococcus pyogenes isolates from patients with invasive and noninvasive infections or from asymptomatic carriers were genetically typed. Sequencing of drs (distantly related sic [streptococcal inhibitor of complement]) genes identified two novel alleles and revealed a polymorphism for drs similar to that of sic . No association was observed between the five different drs alleles and the five restriction patterns of the vir regulon for the isolates studied. These data suggest that drs sequencing may be useful for further differentiation of S. pyogenes isolates with emm12 and identical vir regulon restriction patterns.