Dissemin is shutting down on January 1st, 2025

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BioMed Central, Genome Biology, 12(9), p. 244

DOI: 10.1186/gb-2008-9-12-244

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Replication forks, chromatin loops and dormant replication origins

Journal article published in 2008 by J. Julian Blow ORCID, J. Julian Blow, Xin Quan Ge
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.