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Hindawi, Advances in Pharmacological Sciences, (2011), p. 1-7, 2011

DOI: 10.1155/2011/254619

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The Pharmacology of Acute Lung Injury in Sepsis

Journal article published in 2011 by Brian Michael Varisco ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Acute lung injury (ALI) secondary to sepsis is one of the leading causes of death in sepsis. As such, many pharmacologic and nonpharmacologic strategies have been employed to attenuate its course. Very few of these strategies have proven beneficial. In this paper, we discuss the epidemiology and pathophysiology of ALI, commonly employed pharmacologic and nonpharmacologic treatments, and innovative therapeutic modalities that will likely be the focus of future trials.