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American Society for Microbiology, Journal of Clinical Microbiology, 8(45), p. 2740-2742, 2007

DOI: 10.1128/jcm.01093-07

American Urological Association (AUA), The Journal of Urology, 4S(183), 2010

DOI: 10.1016/j.juro.2010.02.913

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Contribution of a new mutation in parE to quinolone resistance in extended-spectrum-β-lactamase-producing Escherichia coli isolates

Journal article published in 2007 by Antonio Sorlozano ORCID, Jose Gutierrez, Antonio Jimenez, Juan de Dios Luna, J. Luna ORCID, José Luis L. Martínez
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Mutations in the quinolone resistance-determining regions of gyrA , gyrB , parC , and parE were studied in 30 fluoroquinolone-resistant clinical isolates of Escherichia coli producing extended-spectrum β-lactamases. Ten isolates showed a mutation in parE that was significantly associated with an increase in the MIC for fluoroquinolones.