Dissemin is shutting down on January 1st, 2025

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Springer Verlag, Inflammopharmacology, 6(20), p. 307-314

DOI: 10.1007/s10787-011-0107-3

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A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit

This paper is available in a repository.
This paper is available in a repository.

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Abstract

The anticancer effects of traditional Chinese medicine (TCM) have attracted the attention of the public vis-a-vis existing cancer therapies with various side effects. Lycium barbarum fruit, commonly known as Gou Qi Zi in China, is a potential anticancer agent/adjuvant. Its major active ingredients, L. barbarum polysaccharides (LBP), scopoletin and 2-O-b-D-glucopyranosyl-L-ascorbic acid (AA-2bG), are found to have apoptotic and antiproliferative effects on cancer cell lines. Moreover, LBP also contributes to body's immunomodulatory effects and enhances effects of other cancer therapies. It is not known whether there are any undesirable effects. Further studies on its pharmacological mechanisms and toxicology could facilitate a safe usage of this TCM herb. ; Department of Applied Biology and Chemical Technology