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Royal Society of Chemistry, Chemical Science, 5(7), p. 3298-3303, 2016

DOI: 10.1039/c6sc00045b

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A designed DNA binding motif that recognizes extended sites and spans two adjacent major grooves

Journal article published in 2016 by Jessica Rodríguez, M. Eugenio Vázquez ORCID, Jesús Mosquera, Rebeca Garcia-Fandiño ORCID, Vázquez Me, Jose Luis Mascareñas ORCID, M. Eugenio Vázquez, Mascareñas Jl
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We report the rational design of a DNA-binding peptide construct composed of the DNA-contacting regions of two transcription factors (GCN4 and GAGA) linked through an AT-hook DNA anchor.