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Elsevier, Respiratory Medicine Case Reports, (18), p. 35-36, 2016

DOI: 10.1016/j.rmcr.2016.03.006

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Sulfasalazine: A rare cause of acute eosinophilic pneumonia

Journal article published in 2016 by P. Nadarajan, A. Fabre ORCID, E. Kelly
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias . Pulmonary toxicity from sulfasalazine is a rather rare finding. Here, we present the case of a patient who developed acute eosinophilic pneumonia with sulfasalazine use.