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Oxford University Press, Open Forum Infectious Diseases, 1(3), 2016

DOI: 10.1093/ofid/ofw031

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Detection of vaccine induced antibodies to Ebola virus in Oral Fluid

Journal article published in 2016 by Teresa Lambe, Tommy Rampling ORCID, Dhan Samuel, Georgina Bowyer, Katie J. Ewer, Navin Venkatraman, Matthew Edmans, Steve Dicks, Adrian V. S. Hill, Richard S. Tedder, Sarah C. Gilbert
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.