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Elsevier, EBioMedicine, (7), p. 221-229, 2016

DOI: 10.1016/j.ebiom.2016.03.020

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Changes in Neurocognitive Architecture in Patients with Obstructive Sleep Apnea Treated with Continuous Positive Airway Pressure

Journal article published in 2016 by Ivana Rosenzweig, Martin Glasser, William R. Crum, Matthew J. Kempton ORCID, Milan Milosevic, Alison McMillan, Guy D. Leschziner ORCID, Veena Kumari ORCID, Peter Goadsby, Anita K. Simonds, Steve C. R. Williams, Mary J. Morrell
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Obstructive sleep apnea (OSA) is a chronic, multisystem disorder that has a bidirectional relationship with several major neurological disorders, including Alzheimer's dementia. Treatment with Continuous Positive Airway Pressure (CPAP) offers some protection from the effects of OSA, although it is still unclear which populations should be targeted, for how long, and what the effects of treatment are on different organ systems. We investigated whether cognitive improvements can be achieved as early as one month into CPAP treatment in patients with OSA.