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Wiley, ChemMedChem, 5(2), p. 631-635, 2007

DOI: 10.1002/cmdc.200600258

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ESI-MS characterisation of protein adducts of anticancer ruthenium(II)-arene PTA (RAPTA) complexes

Journal article published in 2007 by Angela Casini, Guido Mastrobuoni, Wee Han Ang, Chiara Gabbiani ORCID, Giuseppe Pieraccini, Gloriano Moneti, Paul J. Dyson, Luigi Messori ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Electrospray ionization mass spectrometry allows a rapid characterisation of the adducts formed between three novel anticancer ruthenium(II)-arene PTA compounds and horse heart cytochrome c or hen egg white lysozyme. Specific information on the nature of the protein-bound metallic fragments and the extent of protein metallation was readily obtained.