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Public Library of Science, PLoS ONE, 5(10), p. e0127536, 2015

DOI: 10.1371/journal.pone.0127536

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Direct Detection by the Xpert MTB/RIF Assay and Characterization of Multi and Poly Drug-Resistant Tuberculosis in Guinea-Bissau, West Africa

Journal article published in 2015 by Paulo Rabna, Jorge Ramos, Gema Ponce, Lilica Sanca, Morto Mané, Ana Maria Armada, Diana Machado, Fina Vieira, Victor F. Gomes, Elisabete Martins, Raffaella Colombatti, Fabio Riccardi, João Perdigão, Joana Sotero, Isabel Portugal and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

This study aimed to evaluate the usefulness of the Xpert MTB/RIF assay for the rapid direct detection of M. tuberculosis complex (MTBC) strains and rifampicin resistance associated mutations in a resource-limited setting such as Guinea-Bissau and its implications in the management of tuberculosis (TB) and drug resistant tuberculosis, complementing the scarce information on resistance and genotypic diversity of MTBC strains in this West African country.