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Cell Press, Cell Metabolism, 4(13), p. 361-366, 2011

DOI: 10.1016/j.cmet.2011.03.010

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Unraveling the Biological Roles of Reactive Oxygen Species

Journal article published in 2011 by Michael P Murphy, Arne Holmgren, Nils-Göran Larsson ORCID, Barry Halliwell, Christopher J Chang, Balaraman Kalyanaraman, Sue Goo Rhee, Paul J Thornalley, Linda Partridge, David Gems, Thomas Nyström, Vsevolod Belousov, Paul T Schumacker, Christine C Winterbourn
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Reactive oxygen species are not only harmful agents that cause oxidative damage in pathologies, they also have important roles as regulatory agents in a range of biological phenomena. The relatively recent development of this more nuanced view presents a challenge to the biomedical research community on how best to assess the significance of reactive oxygen species and oxidative damage in biological systems. Considerable progress is being made in addressing these issues, and here we survey some recent developments for those contemplating research in this area.