Elsevier, Radiotherapy & Oncology, 2(119), p. 265-275, 2016
DOI: 10.1016/j.radonc.2016.02.028
Full text: Unavailable
Radiation-induced autophagy is believed to represent a radioprotective mechanism of cancer cells. Thus, its inhibition should support radiation treatment and increase its efficacy. On the other hand, there is evidence that radiation alone or in combination with various chemical agents can induce autophagy that results into increased cell death, especially within transformed apoptosis-resistant cells.