Cell Press, Cell Metabolism, 3(23), p. 401-402, 2016
DOI: 10.1016/j.cmet.2016.02.014
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Paternal diet influences offspring metabolism, yet the underlying epigenetic mechanisms are unclear. Recently, Chen et al. (2016) and Sharma et al. (2016) identified tRNA fragments in sperm and the male reproductive tract as possible inherited factors altered by paternal diet that lead to gene misexpression and altered metabolism in offspring.