Published in
Oxford University Press, Open Forum Infectious Diseases, 1(3), 2016
DOI: 10.1093/ofid/ofw023
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Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
Journal article published in 2016 by
Krishna P. Reddy,
Ednan K. Bajwa,
Robert A. Parker,
Andrew B. Onderdonk,
Rochelle P. Walensky 
This paper is made freely available by the publisher.
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Abstract
Abstract Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis.