Artichoke wastes from the canning industry are rich in phenolic compounds, which can be used as food additives. This his study aims to evaluate the potential of sequential process based on the use of ultrasound extraction and membrane technology for phenolic recovery. In the extraction step, solvent composition and ultrasound power were evaluated to understand their impact on phenolic content and antioxidant capacity. The highest yields were observed for extracts with higher ethanol content (50 and 75%). Therefore, these extracts were selected for concentration by nanofiltration in a tangential module, using differents membranes (NF270, DK and DL). The flux decrease and the phenolic retention were evaluated. Hermia’s models and membrane surface characterization were used to investigate the fouling. The highest flux was observed for extracts with 50% of ethanol, and a retention higher than 95% of chlorogenic acid was observed in this process. DK membrane showed to be less susceptible to fouling, although the cake formation occurred in all evaluated membranes. The most suitable process condition to obtain the highest phenolic yields was extraction with 50% ethanol and an ultrasound power of 240 W and extracts nanofiltration using DK membrane.