Published in
Elsevier, Practical Laboratory Medicine, (5), p. 6-13, 2016
DOI: 10.1016/j.plabm.2016.02.001
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Evaluation of the highly sensitive Roche thyroglobulin II assay and establishment of a reference limit for thyroglobulin-negative patient samples
Journal article published in 2016 by
Dorien M. Rotteveel de Groot,
H. Alec Ross,
H. Alec Ross,
Marcel J. R. Janssen,
Romana T. Netea Maier,
Janine D. Oosting,
Fred C. G. J. Sweep 
,
Antonius E. van Herwaarden
,
Antonius E. van Herwaarden
This paper is made freely available by the publisher.
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Abstract
Thyroglobulin (Tg) measurements are used to monitor for residual thyroid tissue in patients with differentiated thyroid cancer (DTC) after thyroidectomy and radioiodine ablative therapy. In recent years highly sensitive Tg assays have been developed. In this study the analytical performance of the new Roche Elecsys Tg II assay was evaluated and compared with the well documented Access2 Tg assay (Beckman-Coulter).