The supplementary text addresses different details of our study: the error characteristics in different tissues, the amount of non-informative genes, gene rankings of single genes, spot patterns of randomized expression data, gene set overrepresentation and alternative spot selection, GSZ-enrichment of selected spots in selected tissues and the selection of gene sets using global lists and gene set. Furthermore, the results of gene set analysis of subsets of tissues (zoom-in) and different summary reports are provided (Additional file 6).