Not only do humans spend their lives in a densely woven web of meanings, but they also need and want meaning. Although there are a variety of reasons for why this is the case, the current chapter focuses on the function of meaning as an existential anxiety buffer. We argue that the relentless search for meaning is motivated, to a significant extent, by the uniquely human awareness of mortality. As our review of the literature reveals, meaning, at different levels of abstraction, effectively assuages the potential terror born from this awareness.