The purpose of this study is production and characterization of biofilms that possess mechanical properties of synthetic polymers and biocompatibility of the natural ones, being suitable for cell grows.Two types of collagen hydrolysates the acid(HA)and the neutral forms were used as natural macromolecule and poly(vinyl alcohol–PVA)as a synthetic matrix, in order to obtain biofilms. As characterization methods FTIR Spectrometry, Atomic Force Microscopy(AFM), Differential scanning calorimetric measurements and Atomic Absorption Spectroscopy were used.The correlation of the collagen content, the structure and properties of the bioartificial polymers is discussed.