Published in
Elsevier, Colloids and Surfaces B: Biointerfaces, (141), p. 311-317
DOI: 10.1016/j.colsurfb.2016.01.058
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Nanoparticles prolong N-palmitoylethanolamide anti-inflammatory and analgesic effects in vivo
Journal article published in 2016 by
Diana Tronino,
Alessia Offerta,
Carmine Ostacolo 
,
Roberto Russo,
Carmen De Caro,
Antonio Calignano,
Carmelo Puglia,
Paolo Blasi
,
Roberto Russo,
Carmen De Caro,
Antonio Calignano,
Carmelo Puglia,
Paolo Blasi
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Abstract
N-palmitoylethanolamide showed great therapeutic potential in the treatment of inflammation and pain but its unfavourable pharmacokinetics properties will hinder its use in the clinical practice.