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Springer, Diabetologia, 9(56), p. 1884-1887, 2013

DOI: 10.1007/s00125-013-2959-0

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Setting the record straight on TIDE: A lost opportunity for patients with diabetes

Journal article published in 2013 by Zubin Punthakee, Jackie Bosch ORCID, Hertzel C. Gerstein
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Much has been written regarding the recently discontinued Thiazolidinedione Intervention with Vitamin D Evaluation (TIDE) trial (ClinicalTrials.gov NCT00879970; Diabetologia 55: 36-45) and a variety of opinions have been advanced regarding its purpose, context and design (N Engl J Med 397: 959-964). As such, we deemed it appropriate to clarify TIDE's objectives, research questions and design and the clinical equipoise regarding its research questions.