Oxford University Press (OUP), Bioinformatics, 9(25), p. 1118-1124
DOI: 10.1093/bioinformatics/btp131
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Motivation: Novel high-throughput sequencing technologies pose new algorithmic challenges in handling massive amounts of short-read, high-coverage data. A robust and versatile consensus tool is of particular interest for such data since a sound multi-read alignment is a prerequisite for variation analyses, accurate genome assemblies and insert sequencing.