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Nature Publishing Group, Nature Clinical Practice Cardiovascular Medicine, 2(4), p. 60-61, 2007

DOI: 10.1038/ncpcardio0775

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The next frontier in cardiovascular developmental biology—an integrated approach to adult disease?

Journal article published in 2007 by Roger R. Markwald, Jonathan T. Butcher ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

For centuries, clinicians and basic scientists worked side by side in a common quest to iden- tify, understand, and heal the sicknesses of the day. Since the mid-twentieth century, however, a wedge has been slowly driven between these disciplines. Clinicians, constrained by demands incumbent on newly survivable conditions and an ever increasing knowledge base, have become inhibited from participating in basic scientific inquiry, while basic scientists have increasingly pursued more focused studies that result in less clinical translation. These trends are disturbing because of the fundamental need each profes- sion has for the other. One clear example of the interdependent nature of these disciplines is developmental biology. Before the advent of powerful imaging techniques, such as ultrasound