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Royal Society of Chemistry, RSC Advances, 17(6), p. 14059-14067

DOI: 10.1039/c5ra24023a

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Tuning the Nitric Oxide Release from CPO-27 MOFs

Journal article published in 2016 by Damiano Cattaneo, Stewart J. Warrender, Morven J. Duncan, Christopher J. Kelsall, Mary K. Doherty ORCID, Phillip D. Whitfield, Ian L. Megson, Russell E. Morris
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications.