Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship
Journal article published in 2005 by
Pedro Dorado,
Roland Berecz,
Macarena C. Cáceres,
Idilio González,
Jesús Cobaleda,
Adrián LLerena 
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Abstract
AbstractThe drug-metabolizing cytochrome P450 (CYP) enzyme CYP2D6 is involved in the metabolism of several clinically important drugs. So far more than 50 different