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Nature Research, Nature Medicine, 6(11), p. 602-603, 2005

DOI: 10.1038/nm0605-602

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Gateway to the metabolic syndrome

Journal article published in 2005 by Gema Medina-Gomez ORCID, Antonio Vidal-Puig
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A high-fat diet can lead to insulin resistance and the development of the metabolic syndrome, a condition associated with diabetes, heart disease and other ailments. A G-protein-coupled receptor on the surface of insulin-secreting cells in the pancreas senses lipids and may promote the metabolic syndrome under high-fat conditions.