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Dove Press, Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, p. 365

DOI: 10.2147/dmso.s50105

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Radiographic evaluation of the effect of obesity on alveolar bone in rats with ligature-induced periodontal disease

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

There is evidence that the lack of metabolic control of obese patients may accelerate periodontitis. The aim of this study was to evaluate radiographically the effect of cafeteria-diet-induced obesity on alveolar bone loss in rats subjected to periodontal disease. Twenty male Wistar rats were randomly divided into four groups: 1) control group, 2) control and ligature group; 3) cafeteria group; and 4) cafeteria and ligature group. The animals were evaluated for obesity and euthanized, and the mandible of each rat was removed to perform a radiographic evaluation of alveolar bone loss and its effect on diet-induced obesity. The results showed greater alveolar bone loss in the mice in Group 4 (P<0.01). Thus, we concluded that obese mice, on average, showed greater radiographic evidence of alveolar bone loss than mice undergoing induction of obesity.