Results of vibrioflora monitoring and sanitary-hygienic state of the surface water reservoirs in Priamurie in 2011-2013 were analyzed and also Vibrio cholerae eltor detection at the given territory during the seventh pandemic was retrospectively estimated. It was shown that Vibrio cholerae eltor strains were isolated from surface water reservoirs in the Amur region in 1979, 1981 and 1983 whereas the strain isolation in Khabarovsk Territory lasted throughout the period of supervision with separate pauses. On the basis of the V. cholerae analysis for the last three years the presence of optimum conditions for V. cholerae persistence in some surface water reservoirs of Khabarovsk Territory was concluded. It defines the necessity for enhancement of anti-cholera measures after the high water period.